HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400042285, designated StHMG1 on potato chromosome 9, encodes a 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, an enzyme with hydroxymethylglutaryl-CoA reductase (NADPH) activity and protein binding capability. This gene is associated with the mevalonate (MVA) pathway, isoprenoid metabolism and its regulation, sterol and triterpenoid anabolism, phytoalexin and saponin biosynthesis, systemic acquired resistance, response to jasmonic acid and wounding, flower development, and signal transduction. StHMG1 has been connected to steroidal glycoalkaloid content, plant height, biomass, flowering time, male fertility, senescence, pathogen and herbivore resistance, and photosynthetic rate. The encoded protein localises to the ER, peroxisome, chloroplast and nuclear membranes. Studies of related genes in other species link the HMG family to isoprenoid biosynthesis, phytosterol content, and mevalonate pathway regulation.
Annotations
- Chromosome
- 9
- Related genes
- HMG1, HMG2
- GO terms
- protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, Chloroplast Membrane, Systemic Acquired Resistance, Flower Development, Response To Wounding, Response To Jasmonic Acid
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development