HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400043537 (StHMG1) on potato chromosome 12 encodes a hydroxymethylglutaryl-CoA reductase (NADPH) with an HMG_CoA_Rdtase domain, a key enzyme in the mevalonate pathway. This gene is associated with the regulation of isoprenoid metabolism, sterol and triterpenoid anabolism, phytoalexin biosynthesis, and systemic acquired resistance. It is linked to responses to jasmonic acid and wounding, as well as flower development and signal transduction. The encoded protein localizes to multiple membranes including the ER, plastid, peroxisome, and mitochondrial membranes. StHMG1 is associated with steroidal glycoalkaloid content in potato, and associations with plant height, biomass, flowering time, male fertility, senescence, and pathogen and herbivore resistance have been reported. Studies of related genes in other species link the family to isoprenoid biosynthesis, phytosterol content, and mevalonate pathway regulation.
Annotations
- Chromosome
- 12
- Related genes
- HMG1, HMG2
- GO terms
- protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, Systemic Acquired Resistance, Flower Development, Mitochondrial Membrane, Response To Wounding, Response To Jasmonic Acid
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development