SEN1 — Solanum tuberosum

Summary

PGSC0003DMG401003373 (SEN1) on potato chromosome 6 encodes a tRNA-intron lyase (EC 4.6.1.16) with nuclease activity and nucleic acid binding, belonging to the tRNA-intron endonuclease family. The gene is associated with tRNA processing, including intron splice site recognition and cleavage, as well as mRNA processing and defense responses. SEN1 has been directly linked to resistance to Synchytrium endobioticum and potato wart disease in this species. It is also associated with phosphate starvation response, hypocotyl elongation, zygote division, senescence, leaf senescence, and plant defence response. The encoded protein localizes to the SEN complex, membrane, mitochondria, cytoplasm, and nucleus. Related genes in other species link the family to tRNA splicing, stem senescence, leaf senescence, chlorophyll content, and root morphology traits.