HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400047267, designated StHMG1 on potato chromosome 11, encodes a 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, a member of the HMG_CoA_Rdtase family with hydroxymethylglutaryl-CoA reductase (NADPH) activity and protein binding capability. The gene is associated with the mevalonate (MVA) pathway, isoprenoid metabolism, sterol and triterpenoid anabolism, phytoalexin biosynthesis, and systemic acquired resistance. It is linked to responses to jasmonic acid and wounding, as well as flower development and signal transduction. StHMG1 is associated with steroidal glycoalkaloid content in potato, and associations include plant height, biomass, flowering time, male fertility, senescence, and pathogen and herbivore resistance. The encoded protein localises to the ER, peroxisome, chloroplast and nuclear membranes. Studies of related genes in other species link the family to isoprenoid biosynthesis, phytosterol content, and mevalonate pathway regulation.
Annotations
- Chromosome
- 11
- Related genes
- HMG1, HMG2
- GO terms
- protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, Chloroplast Membrane, Systemic Acquired Resistance, Flower Development, Response To Wounding, Response To Jasmonic Acid
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development