HMG1 — Solanum tuberosum
Summary
PGSC0003DMG400045253 (StHMG1) on potato chromosome 12 encodes a hydroxymethylglutaryl-CoA reductase (HMGR) with NADPH activity, a key enzyme of the mevalonate (MVA) pathway. The gene is associated with the regulation of isoprenoid, sterol, triterpenoid, saponin, and phytoalexin biosynthesis, as well as primary and secondary metabolism, CoA metabolism, and protein synthesis. It has been linked to systemic acquired resistance, responses to jasmonic acid and wounding, signal transduction, and flower development. The encoded protein localises to the ER, peroxisome, chloroplast, and nuclear membranes. StHMG1 is associated with steroidal glycoalkaloid content, plant height, biomass, flowering time, male fertility, senescence, and herbivore resistance. Studies of related genes in other species link the HMGR family to isoprenoid biosynthesis, phytosterol content, and mevalonate pathway regulation.
Annotations
- Chromosome
- 12
- Related genes
- HMG1, HMG2
- GO terms
- protein synthesis, regulation of isoprenoid metabolism, secondary metabolism, Chloroplast Membrane, Systemic Acquired Resistance, Flower Development, Response To Wounding, Response To Jasmonic Acid
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development