HSD2 — Phaseolus vulgaris

Summary

PvHSD2 (PHAVU_002G285200) on French bean chromosome 2 encodes a member of the short-chain dehydrogenase/reductase (SDR) family with NAD(P)-binding domains, annotated as a 17-beta-hydroxysteroid dehydrogenase (NADP+) and estradiol 17-beta-dehydrogenase, and also associated with zerumbone synthase, (+)-borneol dehydrogenase, secoisolariciresinol dehydrogenase, and xanthoxin dehydrogenase activities. The gene is associated with steroid metabolism, abscisic acid biosynthesis, monoterpenoid and lignan biosynthesis, and responses to UV, jasmonic acid, and wounding. It is linked to embryogenesis, pollen development, and male gametophyte viability. The encoded protein localizes to oil bodies, mitochondria, cytosol, and membranes. Studies of related genes in other species link the family to seed dormancy.