CAD2 — Phaseolus vulgaris

Summary

PHAVU_002G289200, designated PvCAD2 on chromosome 2 of French bean (Phaseolus vulgaris), encodes a glutamate-cysteine ligase. The gene is associated with glutathione anabolism and is linked to defense responses against insects, bacteria, and fungi, as well as responses to cadmium, ozone, heat, and jasmonic acid. It is associated with pathogen resistance, disease resistance, auxin transport, basal thermotolerance, shoot branching, root development, cadmium tolerance, anthocyanin accumulation, embryo development, and leaf senescence. The encoded protein localizes to the chloroplast stroma, plastid, and cytosol. Studies of related genes in other species link the family to glutathione content, cadmium sensitivity, flowering time, and nematode resistance.