BIP — Phaseolus vulgaris

Summary

PHAVU_002G301304 (PvBIP) encodes a member of the Hsp70 family, containing ATPase and peptide-binding domains characteristic of luminal-binding proteins (BiP). It is annotated with protein folding chaperone activity and heat shock protein binding, and is associated with the unfolded protein response, ERAD pathway, and protein storage. The gene is linked to numerous traits including seed coat color and pattern, root hair length, stomatal resistance, temperature stress response, osmotic sensitivity, auxin and abscisic acid sensitivity, flowering time, disease tolerance, and plant growth and development. It localizes to the ER lumen, transport vesicles, and root hair tips. Studies of related genes in other species connect the family to cadmium stress tolerance, seed germination, and embryo viability, while tomato studies link it to basal defense.