NSH2 — Phaseolus vulgaris

Summary

PHAVU_003G000600 (PvNSH2) on chromosome 3 of French bean encodes a protein with an inosine/uridine hydrolase domain and purine nucleosidase, uridine hydrolase, and inosine nucleosidase activities, along with UDP-glucosyltransferase and protein-binding functions. It is associated with nucleotide salvage, ureide anabolism, ribonucleoside and inosine breakdown, leaf senescence, and seedling development, and localizes to the cytosol. The gene is linked to uridine degradation, purine catabolism, and senescence. Studies of related genes in other species connect the NSH2 family to purine nucleotide catabolism and petal senescence.