NHX8 — Phaseolus vulgaris

Summary

PHAVU_002G185150, designated PvNHX8, encodes a member of the cation/H+ exchanger CPA1 family with lithium:proton antiporter, potassium:proton antiporter and sodium:hydrogen exchanger activities. The product is localised to the vacuolar membrane and plasmalemma. PvNHX8 is associated with lithium export and transport, sodium import, vacuolar membrane transport, cell pH regulation, potassium ion membrane transport and activation of the salinity response. It has been connected to salt tolerance, lithium ion homeostasis and photosynthetic rate. Studies of related genes in other species link the family to lithium tolerance, ion homeostasis, and phenotypes including lithium hypersensitivity with reduced germination and root elongation.

Annotations

Chromosome
2
Related genes
NHX8, NHX1
GO terms
lithium export, sodium import, lithium transport, Potassium:proton Antiporter Activity, cell pH regulation, sodium:hydrogen exchanger, plasmalemma, GO:0009507
Publications
16460505, 17882512, 15489341, 36498877, 33946260, 32295026, PMID:27148284, 33193539
Traits
Lithium Hypersensitive, Reduced Germination and Root Elongation, lithium tolerance, ion homeostasis, salt tolerance, lithium ion homeostasis, lithium homeostasis, net photosynthetic rate, root length