FLS2 — Phaseolus vulgaris

Summary

PHAVU_002G196200, designated PvFLS2, encodes a transmembrane receptor protein serine/threonine kinase with leucine-rich repeat domains, characteristic of plant receptor-like kinases. In French bean, this gene is associated with detection of bacteria, regulation of defence responses to bacteria and oomycetes, and modulation of immune responses including downregulation of immunity and negative regulation of the hypersensitive response. It is linked to salicylic acid-mediated signalling, systemic acquired resistance, and antiviral responses. Associations extend to agronomically relevant traits such as bacterial blight disease resistance, drought stress tolerance, water stress response, biomass yield, spikelet fertility, days to flowering, and vegetative growth time. The gene is also connected to calcium ion homeostasis, endocytosis, and ER tubular network organisation. Studies of related genes in other species link the family to flagellin perception, broad-spectrum disease resistance, and susceptibility to bacterial pathogens.