AGR — Nicotiana attenuata

Summary

A4A49_43119 (AGR, also known as PIN1C) in coyote tobacco (Nicotiana attenuata) encodes a PIN-family auxin efflux carrier, a transmembrane transporter with auxin efflux and influx activities, and also possesses inositol-1,4-bisphosphate 1-phosphatase and 3'(2'),5'-bisphosphate nucleotidase activities. The gene is associated with auxin signalling, root gravitropism, regulation of seed size, and reproductive structure development. It is linked to numerous traits including gravity response, phototropism, leaf vein morphology, shoot growth angle, stamen and anther morphology, seed set percent, auxin content, brassinosteroid content, and responses to blue light, manganese, and osmotic stress. The encoded protein localises to the auxin efflux carrier complex, basal and lateral plasma membranes, recycling endosomes, and clathrin-coated vesicles, and is associated with processes such as tropism, anthocyanin accumulation in response to UV light, and regulation of endocytosis and cell wall organisation.