ATR2 — Nicotiana attenuata

Summary

A4A49_42322 (ATR2, MYC2) in coyote tobacco (Nicotiana attenuata) encodes a protein of the AIB/MYC-like family, with annotated molecular functions including RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription coactivator and corepressor activity, and histone binding. In this species, MYC2 is associated with nicotine and phenolamide biosynthesis. The gene is linked to numerous biological processes, including regulation of defense response to insect, induced systemic resistance via ethylene signaling, superoxide metabolism, proline metabolism, trichome spacing, and positive regulation of seed maturation. Associations also extend to traits such as herbivore resistance, aluminum tolerance, chilling stress response, submergence tolerance, seed protein content, and various morphological traits including anther, petal, and sepal characteristics. Studies of related genes in other species link the family to drought tolerance, fruit quality, and pathogen resistance.