SHD — Nicotiana attenuata

Summary

A4A49_24019 (symbol SHD, also known as HSC80) on coyote tobacco chromosome 8 encodes a heat shock protein 90 family member with ATP-dependent protein folding chaperone activity and domains including Hsp90_N, HSP90_C and HATPase_C. This gene is associated with diverse biological processes such as viral translation, cellular response to unfolded protein, mitochondrial matrix protein import, respiratory burst involved in defense response, and negative regulation of cellulose anabolism. It is linked to traits including floral organ morphology, seed set percent, submergence tolerance, bacterial and viral disease response, temperature stress response, aphid response, photoperiod-sensitive flowering time, and gibberellin biosynthesis. Localization evidence connects the product to the chloroplast outer membrane, ER lumen, vesicle, and cell periphery. Studies of related genes in other species link the family to thermotolerance, broad-spectrum disease resistance, salinity tolerance, and chloroplast envelope maintenance.