SR1 — Nicotiana attenuata

Summary

A4A49_25083 (SR1, also known as CMTA4) in coyote tobacco (Nicotiana attenuata) encodes a protein with CG-1, ankyrin repeat, IQ motif, and IPT domains. It is a DNA-binding transcription factor and transcriptional co-regulator that binds calmodulin and cis-regulatory regions. This gene is associated with cellular responses to aluminum, cold, and freezing, as well as reactive oxygen species and hydrogen peroxide biosynthesis, cytokinin metabolism, anthocyanin regulation and pigmentation, defense upregulation against insects, pistil development, and exocytosis. It localizes to the nucleus, cytoplasm, and extracellular space. Associations with traits such as seed size, flowering time, leaf senescence, root development, carotenoid and anthocyanin content, and responses to high and low temperature stress have been noted. Studies of related genes in other species link this gene family to immunity, pathogen resistance, salt tolerance, freezing tolerance, and aluminum resistance.