NUT — Nicotiana attenuata

Summary

A4A49_25108 (NUT) in coyote tobacco (Nicotiana attenuata) encodes a non-specific serine/threonine protein kinase with a malectin domain and leucine-rich repeats, classified as EC 2.7.11.1. It exhibits transmembrane receptor protein serine/threonine kinase activity, signaling receptor activity, and binds ATP, steroids, SNAREs, and proteins for homo- and heterodimerization. The gene is associated with responses to UV-A and UV light, autophagy, lignin anabolism, microtubule bundling, megasporogenesis, microsporogenesis, stomatal complex morphogenesis, anther wall tapetum development, skotomorphogenesis, regulation of stomatal complex development and cell growth, lateral root development, virus-induced PTGS, detection of brassinosteroid stimulus, hormone-mediated signaling, and secretion. It localizes to the plasma membrane, endosome, and macromolecular complexes. Associations with leaf relative water content, self-incompatibility, and drought tolerance have been noted. Studies of related genes in other species link the family to brassinosteroid perception and stress responses.