ZTL — Nicotiana attenuata

Summary

A4A49_26018 (ZTL) in coyote tobacco (Nicotiana attenuata) encodes a protein with F-box, PAS, and Kelch domains that is annotated as a blue, red, and far-red light photoreceptor and a DNA-binding transcription repressor. It is associated with photoentrainment of the circadian clock, temperature compensation of the circadian clock, shade avoidance, nicotine biosynthesis, and herbivore resistance. The gene is linked to numerous traits including photoperiod sensitivity, blue light sensitivity, UV light sensitivity, leaf area, leaf angle, seed set, fruit set, vegetative vigor, and abscisic acid concentration. It is associated with the upregulation of systemic acquired resistance and shade avoidance, as well as the downregulation of innate immune response and lateral root development. Studies of related genes in other species link the family to circadian regulation, photoperiodic flowering, floral initiation, and drought stress tolerance.