NIC1 — Nicotiana attenuata

Summary

A4A49_25051 (NIC1) in coyote tobacco (Nicotiana attenuata) encodes a protein with an isochorismatase-like domain and nicotinamidase activity. This gene is associated with nicotine metabolism, including response to nicotine, nicotine anabolism, and alkaloid anabolism, as well as pyridine nucleotide salvage, polyamine metabolism, innate immunity, response to abscisic acid, and signal transduction. It is linked to respiration rate and salt stress tolerance. The product localizes to the cytoplasm and nucleus. Studies of related genes in other species link the family to NAD biosynthesis and root growth.