M2 — Nicotiana attenuata

Summary

A4A49_24928 (NaM2) on chromosome 1 of coyote tobacco encodes a cyclophilin-type peptidylprolyl isomerase (CYP40) with cis-trans proline isomerase activity, and is also annotated for GTP:GDP antiporter, U5/U2 snRNA binding, L-serine O-acetyltransferase, cyclosporin A, salicylic acid, histone and chromatin binding, peroxidase activity, and a protein tag. It is associated with nicotine metabolism, cysteine anabolism, the MEP pathway, protein proline isomerization, chaperone-mediated protein complex assembly, alternative mRNA splicing, and responses to chlorate and sulfate starvation. The gene is linked to traits including variegated leaf, starch grain synthesis, leaf length, respiration and photosynthetic rates, sucrose and jasmonic acid content, herbicide and zinc sensitivity, phototropism, root hair length, and chloroplast development. Related genes in other species are associated with water stress tolerance, cold stress response, hydrotropism, phototropism, embryo patterning, and cell polarity.