NUT — Nicotiana attenuata

Summary

A4A49_22586 (NUT) in coyote tobacco (Nicotiana attenuata) encodes a leucine-rich repeat receptor-like protein kinase with transmembrane receptor protein kinase activity, protein serine/threonine kinase activity, and ATP binding. The gene is associated with diverse biological processes including activation of defense response to bacteria, lignin anabolism, autophagy, endocytosis, membrane fission, viral translation, hormone-mediated signaling, heat acclimation, and response to other organisms. It is linked to self-incompatibility. The encoded protein localizes to the plasma membrane, endoplasmic reticulum membrane, cortical ER, perinuclear ER membrane, extracellular region, and nucleus. Studies of related genes in other species connect the family to immune signaling and developmental regulation, though these functions are not yet established for NUT itself.