ERF1 — Nicotiana attenuata

Summary

A4A49_23010 (ERF1/ERF2) in coyote tobacco (Nicotiana attenuata) encodes an AP2/ERF domain-containing transcription factor with sequence-specific DNA binding activity. This gene is associated with the regulation of defense responses, ethylene-mediated signaling, and nicotine anabolism. It has been linked to fruit ripening, seed germination, and responses to thirst and viral genome replication. The encoded protein localizes to the nucleus and protoplasm. Associations with traits include hydrogen peroxide content, heterosis, ethylene sensitivity, photosynthetic rate, and salt tolerance. Phenotypic links encompass nematode resistance, phenolics accumulation, and insect herbivory resistance. Studies of related genes in other species connect the family to abscisic acid sensitivity, cadmium tolerance, heat stress tolerance, bacterial leaf spot resistance, and fruit traits including length, firmness, color, and weight.