PEP — Nicotiana attenuata

Summary

A4A49_22850 (PEP, also known as PAS2A) in coyote tobacco (Nicotiana attenuata) encodes a protein with very-long-chain 3-hydroxyacyl-CoA dehydratase activity (EC 4.2.1.134) and belongs to the Tyr_Pase-like_PTPLA domain family. The gene is associated with very-long-chain fatty acid metabolism and elongation, sphingolipid metabolism, cutin-based cuticle development, suberin biosynthesis, and trichome papilla formation. It has been linked to traits including drought tolerance, salt tolerance, high temperature stress response, chlorophyll content, root length and thickness, root mass density, nitrate transport and uptake, plant male sterility, meristem and embryo development, cell cycle and elongation traits, and leaf composition. The protein localises to the ER membrane, fatty acid elongase complex, cell wall, chloroplast thylakoid membrane, mitochondria, cytosol, and stress granules. Related genes in other species are linked to cell cycle control, cuticular wax formation, and root suberin biosynthesis.