PNH — Lactuca sativa

Summary

LsPNH, located on chromosome 9 of garden lettuce (Lactuca sativa), encodes a protein containing Argonaute, Piwi, and PAZ domains, and is associated with diverse molecular functions including histone ubiquitin ligase and deubiquitinase activities, dsRNA and siRNA binding, RNA endonuclease activity, and superoxide dismutase activity. The gene is linked to numerous biological processes such as miRNA metabolic process, gene silencing by miRNA, somatic stem cell population maintenance, and temporal regulation of development. It has been connected to traits including leaf morphology, leaf polarity, virus resistance, auxin signalling, photosynthetic ability, root phototropism response trait, and UV light sensitivity. Associations with seed dormancy, germination time, flowering time, leaf size, and stomatal index have also been observed. Studies of related genes in other species link the family to shoot meristem organization, leaf and floral development, and fruit yield.