BET9 — Lactuca sativa

Summary

LsBET9 (BET9) on chromosome 9 of garden lettuce encodes a bromodomain-containing protein with GTE_bromo and NET domains. The product exhibits tRNA-adenosine deaminase activity, sequence-specific DNA binding, SUMO transferase activity, histone binding, and transcription coactivator activity. It is associated with tRNA wobble adenosine-to-inosine editing, regulation of nitrate assimilation, salicylic acid metabolism, abscisic acid-mediated signalling, and systemic acquired resistance. The protein localises to the nucleus, cytoplasm, and plant-type vacuole. Associations include traits such as seed protein content, whole plant size, root hair length, flowering time, disease tolerance, and responses to copper, nitrate, aluminum, high and low temperature, oxidative stress, and phosphorus. Phenotypic links include drought tolerance, ABA sensitivity, resistance to Botrytis cinerea, nitrogen use efficiency, and cell cycle regulation. Studies of related genes in other species connect the family to bacterial and virus resistance, lateral root development, and nitrate response.