HSP90 — Lactuca sativa

Summary

LSAT_V11C900503900, the lettuce HSP90 gene on chromosome 9, encodes an ATP-dependent protein folding chaperone with ATP hydrolase and ATP binding activities, belonging to the heat shock protein 90 family. In garden lettuce, this gene is associated with protein stabilization, cellular response to heat, detoxification, and protein folding. The encoded product localizes to the perinuclear region of the cytoplasm, ER lumen, macromolecular complexes, cytosol, plasmalemma, and cytoplasm. Studies of related genes in other species link the HSP90 family to similar chaperone functions, though these associations are not yet established for this specific lettuce gene.