ANS — Lactuca sativa

Summary

LsANS (LSAT_V11C900494900) on chromosome 9 of garden lettuce encodes a 2-oxoglutarate-dependent dioxygenase with leucocyanidin oxygenase, flavonol synthase, and flavanone 3-dioxygenase activities, placing it in the IPNS-like Fe2OG oxygenase family. The gene is associated with anthocyanin, proanthocyanidin, flavonoid, and coumarin biosynthesis, as well as pigment accumulation, vacuole organization, and responses to jasmonic acid, wounding, and fungal molecules. It localizes to the cytosol and cytoplasm. Associations with leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate, stomatal resistance, plant width, shoot dry weight, and UV light sensitivity have been reported. The gene is also linked to cold stress response, nematode susceptibility, and seed pigmentation. Studies of related genes in other species connect the family to flower and fruit color, drought tolerance, and photoprotection.