SHD — Lactuca sativa

Summary

LsSHD, also known as LsHSP90, is a garden lettuce gene on chromosome 9 that encodes a heat shock protein 90 family member, containing Hsp90 and HATPase domains, with ATP-dependent protein folding chaperone activity and additional annotated molecular functions including DNA polymerase, transcription regulator, and pectate lyase activities. The gene is associated with inhibition of cellular response to heat stress, cellular response to unfolded protein, cellular response to brassinosteroid stimulus, base-excision repair, double-strand break repair, and photoentrainment of circadian clock. It is linked to numerous traits including floral organ morphology, seed set percent, bacterial and viral disease responses, aphid response, submergence tolerance, temperature stress response, photoperiod-sensitive flowering time, and plant reproduction traits. The protein localizes to the chloroplast outer membrane, ER lumen, and cell periphery. Related genes in other species are associated with thermotolerance, broad-spectrum disease resistance, salinity tolerance, and developmental regulation.