SHD — Lactuca sativa

Summary

LsSHD, encoded by the gene LSAT_V11C900491700 on chromosome 9 of garden lettuce (Lactuca sativa), is a member of the heat shock protein 90 (HSP90) family, containing Hsp90_N, Hsp90_fam, HSP90_C, and HATPase_C domains, and is annotated with ATP-dependent protein folding chaperone activity. The gene is associated with a wide range of biological processes, including cellular response to unfolded protein, cellular thermotolerance, inhibition of cellular response to heat stress, response to brassinosteroid stimulus, and photoentrainment of the circadian clock. It has been linked to numerous agronomically relevant traits, such as floral organ morphology, seed set percent, seed viability, reproductive growth time, temperature stress response, bacterial and viral disease responses, aphid response, submergence tolerance, and zinc sensitivity. Studies of related genes in other species connect the HSP90 family to thermotolerance, broad-spectrum disease resistance, and salinity tolerance.