ANS — Lactuca sativa

Summary

LsANS, encoded by the gene LSAT_V11C900482010 on chromosome 9 of garden lettuce (Lactuca sativa), is a 2-oxoglutarate-dependent dioxygenase with annotated jasmonic acid hydrolase, ACC oxidase, and flavonol synthase activities. The gene is associated with the regulation of jasmonic acid-mediated signaling, anthocyanin and flavonoid biosynthesis, pigment accumulation, and responses to biotic stresses including defense against fungi, oomycetes, and insects. It is also linked to fruit ripening, ethylene biosynthesis, and cellular responses to fatty acids and toxic substances. Associations with agronomic traits include leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate, stomatal resistance, plant width, and shoot dry weight. Additionally, the gene is connected to drought stress tolerance, oxidative stress, and polycyclic aromatic hydrocarbon sensitivity. Studies of related genes in other species link the family to jasmonic acid response and disease resistance.