30G — Lactuca sativa

Summary

Ls30G (also known as 30G, TFT10, or GF14-MU) on chromosome 9 of garden lettuce encodes a 14-3-3 domain-containing protein. The gene is associated with a wide range of molecular functions including RISC complex binding, glyceraldehyde-3-phosphate dehydrogenase activity, and xylose isomerase activity, among many others. It is linked to biological processes such as positive regulation of miRNA metabolic processes, activation of syringal lignin anabolism, and fumarate metabolism. Associations with agronomically relevant traits include ferulic acid content, starch grain size, zinc content, fruit yield, and spot blotch response. The gene is also connected to phenotypes like iron-deficiency response, low phosphorus stress tolerance, and root growth under alkaline stress. Studies of related genes in other species link the 14-3-3 family to drought sensitivity, tuber sprouting, and fungal disease resistance.