ANS — Lactuca sativa

Summary

LsANS (LSAT_V11C900468440) on chromosome 9 of garden lettuce encodes a 2-oxoglutarate-dependent dioxygenase with jasmonic acid hydrolase, ACC oxidase, flavonol synthase, and flavanone 3-dioxygenase activities. The gene is associated with anthocyanin, flavonoid, coumarin, and ethylene biosynthesis, pigment accumulation, fruit ripening, and regulation of jasmonic acid-mediated signaling. It is linked to downregulation of defense responses to insects, defense responses to fungi and oomycetes, and cellular responses to toxic substances and fatty acids. Associations with plant width, shoot dry weight, leaf color, flavonoid and anthocyanin content, chlorophyll content, photosynthetic rate, and stomatal resistance have been noted. The gene is also connected to drought stress tolerance, spider mite resistance, antifungal resistance, pattern-triggered immunity, and oxidative stress responses. Studies of related genes in other species link the family to jasmonic acid catabolism and disease resistance.