GA5 — Lactuca sativa

Summary

LsGA5 (GA5, GA20OX2) on chromosome 9 encodes a gibberellin 20-oxidase, a 2-oxoglutarate-dependent dioxygenase that also exhibits flavanone 3-dioxygenase activity and binds vitamin C and metal ions. The gene is associated with gibberellin signaling and biosynthesis, regulation of growth, leaf and flower development, and responses to flooding, light stimuli, and defense against oomycetes. It has been linked to plant height, flowering time, seed germination, leaf size, stem height, biomass, fruit set, parthenocarpy, root growth, and salt stress tolerance. Additional associations include ethylene sensitivity, wind tolerance, drought rhizogenesis, graft union formation, thermomorphogenic growth, and adaptation to high altitude. The protein localizes to the cytoplasm. Studies of related genes in other species connect the family to stem growth, fruit development, trichome formation, and salt tolerance.