BET9 — Lactuca sativa

Summary

LsBET9, encoded by the garden lettuce gene LSAT_V11C700382610 on chromosome 7, is a bromodomain-containing protein with GTE and NET domains. It is annotated with DNA-binding transcription factor activity, histone binding, SUMO transferase and binding activities, calmodulin binding, and tRNA-adenosine deaminase activity. The gene is associated with numerous biological processes including regulation of nitrate assimilation, salicylic acid metabolism, abscisic acid signalling, antiviral response, shoot regeneration, and tRNA wobble adenosine-to-inosine editing. It is linked to traits such as seed protein content, flowering time, root morphology, anthocyanin content, disease tolerance, and responses to copper, nitrate, aluminum, auxin, temperature stress, and oxidative stress. Studies of related genes in other species connect the family to resistance to Botrytis cinerea and Pseudomonas syringae, drought tolerance, ABA sensitivity, and nitrogen use efficiency.