CCD4 — Lactuca sativa

Summary

LsCCD4, located on chromosome 6 of garden lettuce (Lactuca sativa), encodes a protein with a carotenoid oxygenase domain and has carotenoid dioxygenase activity and 9-cis-epoxycarotenoid dioxygenase activity, as well as metal binding, mRNA binding, and protein binding. This gene is associated with beta-carotene breakdown, carotene breakdown, beta-carotene anabolism, xanthophyll anabolism, lycopene anabolism, abscisic acid anabolism, abscisic acid metabolism, ethylene anabolism, chloroplast mRNA modification, anther development, regulation of seed germination, response to salicylate, chloroplast organization, fruit ripening, response to gibberellin, seed development, and seed germination. The encoded protein localizes to the chloroplast stroma, cytosol, and nucleus. LsCCD4 is associated with carotenoid content, chloroplast development trait, seed maturation, chlorophyll content, salt tolerance, heat sprouting, tuber morphology, tuber carotenoid content, leaf development, seed β-carotene content, apocarotenoid signaling, leaf senescence carotenoid turnover, leaf carotenoid turnover, elevated carotenoid levels especially β-carotene, seed carotenoid degradation, yellow seedling with altered chloroplast RNA editing, chloroplast RNA editing, palisade cell development, and chloroplast development. Studies of related genes in other species link the family to carotenoid degradation and accumulation, fruit flesh color, and tuber development.