PMIT1 — Lactuca sativa

Summary

LsPMIT1, located on chromosome 6 of garden lettuce (Lactuca sativa), encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, iron, cadmium, and aluminium ion transmembrane transporter activity. The gene is associated with responses to manganese starvation and homeostasis, as well as cadmium, lead, and iron ion transport. It is linked to endosome, vacuolar, and Golgi membranes, and to the plasmalemma and plastid. Associations with agronomic traits include photosynthetic rate, root length, and plant height. The gene is also connected to phenotypes such as growth under manganese deficiency, copper homeostasis, cadmium transport, iron remobilization, manganese uptake, seed germination, and photosystem II activity. Studies of related genes in other species link the family to iron mobilization, manganese homeostasis, pathogen resistance, and cadmium tolerance.