ATM4 — Lactuca sativa

Summary

LsATM4, also known as ATM4, on chromosome 7 of garden lettuce (Lactuca sativa) encodes a Myb-domain protein with DNA binding, transcription factor activity, and protein dimerization activity. It is associated with the regulation of anthocyanin, flavonoid, proanthocyanidin, and glucosinolate biosynthetic processes, as well as raffinose metabolism, trichome morphogenesis and spacing, and defense responses to insects. The gene is linked to drought recovery, cellular detoxification of cadmium ions, and responses to sulfur starvation. It localizes to the nucleus, cytosol, root hair, and preprophase band. Associations with traits include leaf trichome density, seed protein content, shoot elongation under submergence, phosphorus response, iron concentration, and photoperiod-sensitive flowering time. Studies of related genes in other species connect the family to glucosinolate accumulation, cuticle formation, suberin synthesis, and drought response.