PMIT1 — Lactuca sativa

Summary

LsPMIT1, located on chromosome 6 of garden lettuce (Lactuca sativa), encodes a member of the NRAMP family of metal ion transporters. The gene product exhibits transmembrane transporter activity for manganese, iron, cadmium, and aluminium ions. LsPMIT1 is associated with manganese ion homeostasis and transport, cellular responses to manganese and iron, cadmium and lead ion transport, and positive regulation of reactive oxygen species metabolism. It is linked to traits including photosynthetic rate, root length, and plant height, as well as phenotypes such as growth under manganese deficiency, copper homeostasis, cadmium transport, iron remobilization, manganese uptake, root growth, seed germination, and photosystem II activity. The protein localizes to endosome, vacuolar, Golgi, plastid, and plasma membranes.