PMIT1 — Lactuca sativa

Summary

LsPMIT1, also known as NRAMP1-6, encodes a member of the NRAMP family of metal ion transporters on chromosome 6 of garden lettuce. The protein exhibits transmembrane transporter activity for manganese, iron, cadmium, and aluminium ions. It is associated with manganese ion homeostasis and transport, cellular responses to manganese starvation, cadmium and lead ion transport, and iron membrane transport. The gene is linked to positive regulation of reactive oxygen species metabolism and upregulation of unidimensional cell growth. Localisation evidence places the product at the vacuolar membrane, endosome, Golgi, plasmodesma, and plastid. Associations with agronomic traits include photosynthetic rate, root length, and plant height. Phenotypic connections involve growth under manganese deficiency, copper homeostasis, cadmium transport, iron remobilization, seed germination, and photosystem II activity.