PNH — Lactuca sativa

Summary

LsPNH, on lettuce chromosome 6, encodes a Piwi-domain and RNaseH-superfamily protein with diverse annotated molecular functions including histone ubiquitin ligase and deubiquitinase activities, superoxide dismutase activity, dsRNA and siRNA binding, and RNA endonuclease activity. The gene is associated with miRNA metabolic processes, gene silencing by miRNA, somatic stem cell population maintenance, cell fate commitment, and temporal regulation of development. It has been linked to numerous traits including leaf morphology and polarity, virus resistance, auxin signalling, photosynthetic ability, UV light sensitivity, seed dormancy, germination time, root growth, flowering time, and lignin biosynthesis. Studies of related genes in other species connect the family to histone ubiquitination, seed dormancy, leaf colour, flowering time, fruit yield, and axillary bud formation.