CPT — Lactuca sativa

Summary

LsCPT (CPT, HEPS, ZFPS), located on chromosome 5 of garden lettuce (Lactuca sativa), encodes a prenyltransferase with IPPS, zFPS, dimethylallylcistransferase, rubber cis-polyprenylcistransferase, and dehydrodolichyl diphosphate synthase activities, belonging to the UPP_synth-like family. The gene is associated with polyprenol and dolichyl monophosphate anabolism, plastid membrane organization, response to cold, and virus-induced PTGS. Its product localizes to the chloroplast stroma, ER, and mitochondria. LsCPT is associated with reduced long-chain polyisoprenoids and medium-chain-length polyprenol biosynthesis. Studies of related genes in other species connect the family to photosynthetic efficiency, chloroplast membrane dynamics, polyprenol and dolichol biosynthesis, diterpenoid biosynthesis, and cold stress response, with sequence similarity also linking the family to traits including plant height, leaf shape, chlorophyll content, and root yield.