CPT — Lactuca sativa

Summary

LsCPT, encoded by the gene LSAT_V11C500284540 on chromosome 5 of garden lettuce (Lactuca sativa), is a prenyltransferase with isopentenyl diphosphate synthase (IPPS), ZFPS, dimethylallylcistransferase, rubber cis-polyprenylcistransferase, and dehydrodolichyl diphosphate synthase activities. It belongs to the UPP_synth-like protein family and binds magnesium. The gene is associated with polyprenol and dolichyl monophosphate anabolism, plastid membrane organization, virus-induced post-transcriptional gene silencing, and response to cold. Its product localizes to the chloroplast stroma, endoplasmic reticulum, mitochondria, and cytosol. LsCPT has been connected to reduced long-chain polyisoprenoids and medium-chain-length polyprenol biosynthesis. Studies of related genes in other species link the family to photosynthetic efficiency, chloroplast membrane dynamics, cold stress response, and traits including plant height, leaf shape, chlorophyll content, and root yield.

Annotations

Chromosome
5
Related genes
CPT, CPT2, cPT6, CPT7, AT5G58784, HEPS
GO terms
Plastid Membrane Organization, polyprenol anabolism, Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups, dehydrodolichyl diphosphate synthase activity, dolichyl monophosphate anabolism, ER, Mg binding, GO:0009507
Publications
21419101, PMID:19291320, PMID:36605705, PMID:31370240, PMID:15047901, PMID:32727369, PMID:15082927, PMID:25477521
Traits
polyprenol biosynthesis, medium-chain-length polyprenol biosynthesis, Reduced Long Chain Polyisoprenoids (52%), Reduced Long Chain Polyisoprenoids, cold stress response, polyisoprenoid synthesis, photosynthetic efficiency, polyprenol synthesis