CCD4 — Lactuca sativa

Summary

LsCCD4, located on chromosome 6 of garden lettuce (Lactuca sativa), encodes a protein with a Carotenoid_Oase domain and carotenoid dioxygenase activity, 9-cis-epoxycarotenoid dioxygenase activity, and metal binding. This gene is associated with carotenoid and chlorophyll content, chloroplast development and organization, seed maturation and development, and fruit ripening. It is linked to abscisic acid, ethylene, and xanthophyll anabolism, as well as beta-carotene and carotene breakdown. Associations include regulation of seed germination, response to insects, salicylate, and gibberellin, anther development, and chloroplast mRNA modification. The gene is associated with salt tolerance, heat sprouting, tuber morphology and carotenoid content, leaf development and senescence, seed β-carotene content, and apocarotenoid signaling. Studies of related genes in other species link the CCD4 family to carotenoid accumulation, fruit flesh color, and apocarotenoid glycoside biosynthesis.