ANS — Lactuca sativa

Summary

LsANS (LSAT_V11C500282930) on chromosome 5 of garden lettuce encodes a 2-oxoglutarate-dependent dioxygenase with jasmonic acid hydrolase, leucocyanidin oxygenase, flavonol synthase, and flavanone 3-dioxygenase activities. The gene is associated with anthocyanin, flavonoid, and coumarin biosynthesis, pigment accumulation, and regulation of jasmonic acid-mediated signaling. It is linked to downregulation of defense responses to insects, regulation of defense against fungi, and response to oomycetes and fungal molecules. Associations include leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate, stomatal resistance, plant width, and shoot dry weight. The gene is also connected to drought stress tolerance, spider mite resistance, antifungal resistance, pattern-triggered immunity, and oxidative stress responses. Related genes in other species link the family to jasmonic acid response and disease resistance.