BET9 — Lactuca sativa

Summary

LsBET9, encoded by gene LSAT_V11C300142220 on chromosome 3 of garden lettuce (Lactuca sativa), is a bromodomain-containing protein with histone acetylase activity, SUMO transferase activity, and DNA-binding transcription factor activity. It is associated with histone binding, calmodulin binding, and transcription coactivator activity, and localizes to the nucleus, cytoplasm, and plant-type vacuole. The gene is linked to numerous biological processes including regulation of nitrate assimilation, salicylic acid metabolism, antiviral response, shoot regeneration, and developmental growth. Agronomically, LsBET9 has been connected to traits such as seed protein content, flowering time, disease tolerance, root morphology, anthocyanin content, and responses to abiotic stresses including high temperature, oxidative stress, and salinity. Studies of related genes in other species link the family to resistance to Pseudomonas syringae, virus resistance, lateral root development, and nitrogen assimilation.