GT5 — Lactuca sativa

Summary

LsGT5 (GT5), located on chromosome 3 of garden lettuce (Lactuca sativa), encodes a UDP-glycosyltransferase with coniferyl-alcohol, hydroquinone, anthocyanidin 3-O-, and isoflavone 7-O-glucosyltransferase activities. The gene is associated with lignin metabolism, anthocyanin anabolism, sugar-mediated signaling, stomatal closure, seed and leaf development, and salinity response. It has been linked to root morphology, salt tolerance, and reduced ABA sensitivity during seed germination and root elongation. Associations include monolignol glucoside accumulation, sinapoyl malate accumulation, azoxystrobin degradation, wound response, lignification, and phenylpropanoid metabolism. Studies of related genes in other species connect the family to syringin production, azoxystrobin resistance, early flowering, and increased lignin content. The protein localizes to the nucleus and mitochondria.