TPS5 — Lactuca sativa

Summary

LsTPS5 (gene symbol TPS5) on chromosome 4 of garden lettuce encodes a protein with trehalose-phosphatase and transglucosylase activities, containing Glyco_trans_20 and trehalose_PPase domains. It is associated with terpenoid metabolism, mycose biosynthesis, ethylene-mediated signaling, and responses to heat, abscisic acid, and hypoxia. The gene is linked to yield, photosynthetic rate, temperature stress, oxidative stress, and disease tolerance traits. Phenotypic associations include thermotolerance, water-use efficiency, stomatal development and closure, seed germination, sugar signaling, and defense responses to Botrytis cinerea and Pseudomonas syringae. The protein localizes to the cytoplasm, nucleus, mitochondria, and nucleolus. Studies of related genes in other species connect the TPS5 family to trehalose-6-phosphate biosynthesis, carbon utilization, heat tolerance, yield, and bacterial resistance.