CHS — Lactuca sativa

Summary

LsCHS (LSAT_V11C300152950) on lettuce chromosome 3 encodes a protein with chalcone/stilbene synthase and thiolase-like domains and a type III polyketide synthase domain. The enzyme exhibits naringenin-chalcone synthase, chalcone isomerase, flavanone 4-reductase, flavonol synthase, and SUMO transferase activities. It is associated with flavonoid, anthocyanin, polyketide, and sucrose biosynthesis, pollen wall assembly, and responses to UV-B, jasmonic acid, gravity, and heat acclimation. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. LsCHS is linked to traits including anthocyanin content, chlorophyll content, photosynthetic and respiration rates, shoot fresh weight, flowering time, root morphology, and responses to salt, drought, oxidative stress, and UV light. Associations also connect it to male sterility, pollen exine development, root-knot nematode resistance, and genome stability.