CYP71D4 — Lactuca sativa

Summary

LsCYP71D4 (CYP71D4) on lettuce chromosome 3 encodes a cytochrome P450 monooxygenase with germacrene A acid 8beta-hydroxylase and costunolide synthase activities, and is associated with oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen, monooxygenase activity, iron binding, and heme binding. The gene is associated with sesquiterpenoid and lactone metabolism, sesquiterpene biosynthetic process, terpenoid and phenylpropanoid anabolism, and response to jasmonic acid. Its product localizes to membranes. Related genes in other species link the family to additional oxidoreductase activities (EC 1.14.14.170, 1.14.14.168, 1.14.14.150, 1.14.14.151).