LOX — Lactuca sativa

Summary

LsLOX, encoded by the gene LSAT_V11C300113220 on chromosome 3 of garden lettuce (Lactuca sativa), is a lipoxygenase family protein containing the conserved LipOase, PLAT/LH2 and iron-binding domains. It exhibits linoleate 13S-lipoxygenase, peroxidase and phytoene dehydrogenase activities, and is associated with oxylipin and jasmonic acid biosynthesis, green leaf volatile production, and responses to herbivores, insects, ozone and high light intensity. The gene is linked to anther development, photoperiodic flowering, and traits including nitrate content, seed yield, photosynthetic rate, root thickness, and tolerance to low temperature, drought and cadmium stress. It localises to chloroplast thylakoids, the chloroplast envelope, stromules, stress granules and the apoplast. Studies of related genes in other species connect the family to jasmonate-mediated defence, wound response, resistance to fungal pathogens and herbivory, and leaf senescence.