ACHE — Lactuca sativa

Summary

LSAT_V11C300123890, designated ACHE, on garden lettuce (Lactuca sativa) chromosome 3, encodes a GDSL family protein with SGNH hydrolase superfamily domains. The product exhibits sinapine esterase, acetylajmaline esterase, carboxylic ester hydrolase, lipase, and serine O-acyltransferase activities, along with glycosidase activity and IgE binding. This gene is associated with acetylcholine breakdown, isoprenoid anabolism, lipolysis, detoxification, alkaloid metabolism, nodulation, seed germination, response to wounding, and defense response. It is linked to ER organisation and localises to the symbiosome, extracellular region, mitochondria, and cytosol. The gene is also associated with flavonoid content. Studies of related GDSL esterase/lipase family members in other species link the family to germination rate and arsenic concentration.